Cryofibrinogenemia: JCR: Journal of Clinical Rheumatology.
This test looks for an abnormal protein called cryofibrinogen in your blood plasma. People who have this abnormal protein may get a disorder called cryofibrinogenemia. The disorder rarely causes symptoms. But if it is not treated, it can become life-threatening and lead to stroke, heart attack, gangrene.Cryofibrinogenemia is a treatable and potentially reversible disease. In moderate forms, it can be treated by simply avoiding cold temperatures. The use of corticosteroids in association with low-dose aspirin is the treatment of choice for moderate forms, although stanozolol is an alternative maintenance therapy.Classification essays are quite specific in that they deal with organizing classifications and identifying logical links to the classifications. Anyone writing an essay of this type is expected to sort or organize the main points or arguments of their work into categories. It is important to note that categories should be aligned to the topic.
Cryofibrinogen is a cryoprotein first described by Korst and Kratochvil in 1955, that readily forms an insoluble complex at cold temperatures. 1 Unlike cryoglobulin, the precipitate forms only in plasma and not in serum. At high concentrations, cryofibrinogenemia can induce a severe necrotizing vasculopathy.Cryofibrinogenemia is an under-recognized cryoprotein that can be life-threatening. Skin necrosis and thrombotic events are the main complications. Cryofibrinogenemia can be classified as 2 types: a primary (essential) or a secondary form associated with autoimmune disorders, malignancy, and sepsis.
Your healthcare provider will order other tests if your cryofibrinogen test shows that you have cryofibrinogenemia. To diagnose primary cryofibrinogenemia, your provider may order an angiogram to look for blocked arteries. Or he or she may order a biopsy of affected tissue.
